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Zanaflex may also interact with the following medications:

• acyclovir
• alcohol
• antihistamines
• baclofen
• barbiturates like phenobarbital
• benzodiazepines
• cimetidine
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• female hormones, like estrogens or progestins and birth control pills
• medicines for high blood pressure
• medicines for irregular heartbeat
• medicines for pain like codeine, morphine, and hydrocodone
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• zileuton

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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